I am just saying that Frost will stress defenses and conflict coaches by utilizing his personnel differently than others. I think when a defensive coach tries to match up to personnel in the traditional method, he gets taken advantage of, simply because of how interchangeable a lot of his players are. His RB that splits out may have WR skills that will take advantage of most any LB.
Most defenses try to combat the spread with speed, playing sound defense and hoping that they make a mistake and turn the ball over or punt. But putting a fast LB on a guy with WR talent or a fast LB on a TE that has WR talent is dangerous. The same could be said for matching personnel when he brings a WR into the running game, not many people are expecting the WR to be an option in the the running game, when it isn't a reverse. So when they match up traditionally, they are in conflict when the have a corner out there instead of a LB.
I am by no means dumping on Anthony or his charts. They were awesome and full of great detail. I just find the cat and mouse game interesting, and as offenses evolve, it will be interesting if DCs continue to account for personnel the same way.