Some of those are big things. Look its impossible to not make mistakes in a game. Every team is going to miss tackles (and our guys did a great job tonight), you are always going to have penalties.
The issue is that the issues we saw tonight are REPEAT ISSUES. Special teams, snapping blunders. Returning kicks when we can't get to the 20...again and again. Failure to run the ball when its working. Clock issues (although that did not directly hurt us, it is bad to see it yet again!). Rinse, wash, repeat.