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infinity13

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COVID vaccine researchers had previously assumed mRNA COVID vaccines would behave like traditional vaccines. The vaccine’s spike protein — responsible for infection and its most severe symptoms — would remain mostly in the injection site at the shoulder muscle or local lymph nodes.

But new research obtained by a group of scientists contradicts that theory, a Canadian cancer vaccine researcher said last week.

“We made a big mistake. We didn’t realize it until now,” said Byram Bridle, a viral immunologist and associate professor at University of Guelph, Ontario. “We thought the spike protein was a great target antigen, we never knew the spike protein itself was a toxin and was a pathogenic protein. So by vaccinating people we are inadvertently inoculating them with a toxin.”



Bridle, who was awarded a $230,000 grant by the Canadian government last year for research on COVID vaccine development, said he and a group of international scientists filed a request for information from the Japanese regulatory agency to get access to Pfizer’s “biodistribution study.”

Biodistribution studies are used to determine where an injected compound travels in the body, and which tissues or organs it accumulates in.

“It’s the first time ever scientists have been privy to seeing where these messenger RNA [mRNA] vaccines go after vaccination,” Bridle said in an interview with Alex Pierson where he first disclosed the data. “Is it a safe assumption that it stays in the shoulder muscle? The short answer is: absolutely not. It’s very disconcerting.”

The Sars-CoV-2 has a spike protein on its surface. That spike protein is what allows it to infect our bodies, Bridle explained. “That is why we have been using the spike protein in our vaccines,” Bridle said. “The vaccines we’re using get the cells in our bodies to manufacture that protein. If we can mount an immune response against that protein, in theory we could prevent this virus from infecting the body. That is the theory behind the vaccine.”

“However, when studying the severe COVID-19, […] heart problems, lots of problems with the cardiovascular system, bleeding and clotting, are all associated with COVID-19,” he added. “In doing that research, what has been discovered by the scientific community, the spike protein on its own is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.”

When the purified spike protein is injected into the blood of research animals, they experience damage to the cardiovascular system and the protein can cross the blood-brain barrier and cause damage to the brain, Bridle explained.

The biodistribution study obtained by Bridle shows the COVID spike protein gets into the blood where it circulates for several days post-vaccination and then accumulates in organs and tissues including the spleen, bone marrow, the liver, adrenal glands and in “quite high concentrations” in the ovaries.

“We have known for a long time that the spike protein is a pathogenic protein, Bridle said. “It is a toxin. It can cause damage in our body if it gets into circulation.”

A large number of studies have shown the most severe effects of SARS-CoV-2, the virus that causes COVID, such as blood clotting and bleeding, are due to the effects of the spike protein of the virus itself.

A recent study in Clinical and Infectious Diseases led by researchers at Brigham and Women’s Hospital and the Harvard Medical School measured longitudinal plasma samples collected from 13 recipients of the Moderna vaccine 1 and 29 days after the first dose and 1-28 days after the second dose.

Out of these individuals, 11 had detectable levels of SARS-CoV-2 protein in blood plasma as early as one day after the first vaccine dose, including three who had detectable levels of spike protein. A “subunit” protein called S1, part of the spike protein, was also detected.

Spike protein was detected an average of 15 days after the first injection, and one patient had spike protein detectable on day 29 — one day after a second vaccine dose — which disappeared two days later.

The results showed S1 antigen production after the initial vaccination can be detected by day one and is present beyond the injection site and the associated regional lymph nodes.

Assuming an average adult blood volume of approximately 5 liters, this corresponds to peak levels of approximately 0.3 micrograms of circulating free antigen for a vaccine designed only to express membrane-anchored antigen.

In a study published in Nature Neuroscience, lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems. The spike protein also crossed the blood-brain barrier and caused damage to the brain.

It was a grave mistake to believe the spike protein would not escape into the blood circulation, according to Bridle. “Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein — that the vaccine itself, plus the protein — gets into blood circulation,” he said.

Bridle said the scientific community has discovered the spike protein, on its own, is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.

Once in circulation, the spike protein can attach to specific ACE2 receptors that are on blood platelets and the cells that line blood vessels, Bridle said. “When that happens it can do one of two things. It can either cause platelets to clump, and that can lead to clotting — that’s exactly why we’ve been seeing clotting disorders associated with these vaccines. It can also lead to bleeding,” he added.

Both clotting and bleeding are associated with vaccine-induced thrombotic thrombocytopenia (VITT). Bridle also said the spike protein in circulation would explain recently reported heart problems in vaccinated teens.

Stephanie Seneff, senior research scientists at Massachusetts Institute of Technology, said it is now clear vaccine content is being delivered to the spleen and the glands, including the ovaries and the adrenal glands, and is being shed into the medium and then eventually reaches the bloodstream causing systemic damage.

“ACE2 receptors are common in the heart and brain,” she added. “And this is how the spike protein causes cardiovascular and cognitive problems.”

Dr. J. Patrick Whelan, a pediatric rheumatologist, warned the U.S. Food and Drug Administration (FDA) in December mRNA vaccines could cause microvascular injury to the brain, heart, liver and kidneys in ways not assessed in safety trials.

In a public submission, Whelan sought to alert the FDA to the potential for vaccines designed to create immunity to the SARS-CoV-2 spike protein to instead cause injuries.

Whelan was concerned the mRNA vaccine technology utilized by Pfizer and Moderna had “the potential to cause microvascular injury (inflammation and small blood clots called microthrombi) to the brain, heart, liver and kidneys in ways that were not assessed in the safety trials
 
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lolwat

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I saw.. bla bla bla.. may cause blood clots. We heard a handful regarding the AstraZeneca or whatever get blood clots. I also see millions being vaccinated that are not only just fine, but are having the covid infections and deaths drop dramatically.

So get the vax if you haven't already.
 
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damcde

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Firstly, every vaccine is going to have some systemic properties to them. So the first sentence of the article gets off to a great start with a lie.

Secondly, there is a huge huge huge difference between giving an animal an iv injection of an antigen, vs. intramuscular. It is completely asinine to try and directly compare the two scenarios.

Thirdly, the complaint is about the spike protein, which is found in the virus naturally. So you are going to have this problem if you get infected. Except that with a natural infection, you are likely going to have much more inflammation, which amplifies these types of problems. So if you want to compare, the vaccine is going to be way safer.

Finally, you can look at the actual evidence of impact on Spike protein with thromboembolism (which is one of the major things it does). We know that SARS-CoV-2 has the ability to get into the bloodstream from the lungs, and once it does so it causes a lot of problems. There is a pretty high rate thromboembolism (20-30 percent) in . But yet there is no evidence for this mRNA vaccines, and for the viral vector vaccines you are looking at rates of 1-2 per million.


 
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infinity13

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Yes the scientists had an agenda. Preventing COVID deaths.
And what about the scientist that study and question the safety of these vaccine?
Big Pharma has given us no reason to blindly trust them.
 

Oldschool1964

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And what about the scientist that study and question the safety of these vaccine?
Big Pharma has given us no reason to blindly trust them.
OOOhhhhh, THIS is the "Big Switch" the libs like @Hardlyboy, @lolwat talk about. Libs used to be anti-big Pharma and they accused conservatives of being pro-big Pharma, and now conservatives are anti-big Pharma and libs are pro-big Pharma, pro-big business, pro-big censorship. We're living it right now!! I get it. THAT's what they are referring to.
 

huskerj12

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Firstly, every vaccine is going to have some systemic properties to them. So the first sentence of the article gets off to a great start with a lie.

Secondly, there is a huge huge huge difference between giving an animal an iv injection of an antigen, vs. intramuscular. It is completely asinine to try and directly compare the two scenarios.

Thirdly, the complaint is about the spike protein, which is found in the virus naturally. So you are going to have this problem if you get infected. Except that with a natural infection, you are likely going to have much more inflammation, which amplifies these types of problems. So if you want to compare, the vaccine is going to be way safer.

Finally, you can look at the actual evidence of impact on Spike protein with thromboembolism (which is one of the major things it does). We know that SARS-CoV-2 has the ability to get into the bloodstream from the lungs, and once it does so it causes a lot of problems. There is a pretty high rate thromboembolism (20-30 percent) in . But yet there is no evidence for this mRNA vaccines, and for the viral vector vaccines you are looking at rates of 1-2 per million.


I truly respect and admire your posts here, but you should really stop wasting your time trying to reason with people who choose to live in alternate realities.
 
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Red_Hack

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COVID vaccine researchers had previously assumed mRNA COVID vaccines would behave like traditional vaccines. The vaccine’s spike protein — responsible for infection and its most severe symptoms — would remain mostly in the injection site at the shoulder muscle or local lymph nodes.

But new research obtained by a group of scientists contradicts that theory, a Canadian cancer vaccine researcher said last week.

“We made a big mistake. We didn’t realize it until now,” said Byram Bridle, a viral immunologist and associate professor at University of Guelph, Ontario. “We thought the spike protein was a great target antigen, we never knew the spike protein itself was a toxin and was a pathogenic protein. So by vaccinating people we are inadvertently inoculating them with a toxin.”



Bridle, who was awarded a $230,000 grant by the Canadian government last year for research on COVID vaccine development, said he and a group of international scientists filed a request for information from the Japanese regulatory agency to get access to Pfizer’s “biodistribution study.”

Biodistribution studies are used to determine where an injected compound travels in the body, and which tissues or organs it accumulates in.

“It’s the first time ever scientists have been privy to seeing where these messenger RNA [mRNA] vaccines go after vaccination,” Bridle said in an interview with Alex Pierson where he first disclosed the data. “Is it a safe assumption that it stays in the shoulder muscle? The short answer is: absolutely not. It’s very disconcerting.”

The Sars-CoV-2 has a spike protein on its surface. That spike protein is what allows it to infect our bodies, Bridle explained. “That is why we have been using the spike protein in our vaccines,” Bridle said. “The vaccines we’re using get the cells in our bodies to manufacture that protein. If we can mount an immune response against that protein, in theory we could prevent this virus from infecting the body. That is the theory behind the vaccine.”

“However, when studying the severe COVID-19, […] heart problems, lots of problems with the cardiovascular system, bleeding and clotting, are all associated with COVID-19,” he added. “In doing that research, what has been discovered by the scientific community, the spike protein on its own is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.”

When the purified spike protein is injected into the blood of research animals, they experience damage to the cardiovascular system and the protein can cross the blood-brain barrier and cause damage to the brain, Bridle explained.

The biodistribution study obtained by Bridle shows the COVID spike protein gets into the blood where it circulates for several days post-vaccination and then accumulates in organs and tissues including the spleen, bone marrow, the liver, adrenal glands and in “quite high concentrations” in the ovaries.

“We have known for a long time that the spike protein is a pathogenic protein, Bridle said. “It is a toxin. It can cause damage in our body if it gets into circulation.”

A large number of studies have shown the most severe effects of SARS-CoV-2, the virus that causes COVID, such as blood clotting and bleeding, are due to the effects of the spike protein of the virus itself.

A recent study in Clinical and Infectious Diseases led by researchers at Brigham and Women’s Hospital and the Harvard Medical School measured longitudinal plasma samples collected from 13 recipients of the Moderna vaccine 1 and 29 days after the first dose and 1-28 days after the second dose.

Out of these individuals, 11 had detectable levels of SARS-CoV-2 protein in blood plasma as early as one day after the first vaccine dose, including three who had detectable levels of spike protein. A “subunit” protein called S1, part of the spike protein, was also detected.

Spike protein was detected an average of 15 days after the first injection, and one patient had spike protein detectable on day 29 — one day after a second vaccine dose — which disappeared two days later.

The results showed S1 antigen production after the initial vaccination can be detected by day one and is present beyond the injection site and the associated regional lymph nodes.

Assuming an average adult blood volume of approximately 5 liters, this corresponds to peak levels of approximately 0.3 micrograms of circulating free antigen for a vaccine designed only to express membrane-anchored antigen.

In a study published in Nature Neuroscience, lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems. The spike protein also crossed the blood-brain barrier and caused damage to the brain.

It was a grave mistake to believe the spike protein would not escape into the blood circulation, according to Bridle. “Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein — that the vaccine itself, plus the protein — gets into blood circulation,” he said.

Bridle said the scientific community has discovered the spike protein, on its own, is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.

Once in circulation, the spike protein can attach to specific ACE2 receptors that are on blood platelets and the cells that line blood vessels, Bridle said. “When that happens it can do one of two things. It can either cause platelets to clump, and that can lead to clotting — that’s exactly why we’ve been seeing clotting disorders associated with these vaccines. It can also lead to bleeding,” he added.

Both clotting and bleeding are associated with vaccine-induced thrombotic thrombocytopenia (VITT). Bridle also said the spike protein in circulation would explain recently reported heart problems in vaccinated teens.

Stephanie Seneff, senior research scientists at Massachusetts Institute of Technology, said it is now clear vaccine content is being delivered to the spleen and the glands, including the ovaries and the adrenal glands, and is being shed into the medium and then eventually reaches the bloodstream causing systemic damage.

“ACE2 receptors are common in the heart and brain,” she added. “And this is how the spike protein causes cardiovascular and cognitive problems.”

Dr. J. Patrick Whelan, a pediatric rheumatologist, warned the U.S. Food and Drug Administration (FDA) in December mRNA vaccines could cause microvascular injury to the brain, heart, liver and kidneys in ways not assessed in safety trials.

In a public submission, Whelan sought to alert the FDA to the potential for vaccines designed to create immunity to the SARS-CoV-2 spike protein to instead cause injuries.

Whelan was concerned the mRNA vaccine technology utilized by Pfizer and Moderna had “the potential to cause microvascular injury (inflammation and small blood clots called microthrombi) to the brain, heart, liver and kidneys in ways that were not assessed in the safety trials
So not an article based on imperial evidence, but rather assumptions of what could happen, but has not been seen to happen.

Got it.
 
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mhosek

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So not an article based on imperial evidence, but rather assumptions of what could happen, but has not been seen to happen.

Got it.
My take (and for starters I think you were going for ‘empirical’ but got tricked out of it by spellcheck) is rather they were collecting empirical evidence of a finding that was Not supposed to be a result of the vaccines, but in fact showed the vaccine spike protein Did enter the bloodstream, cross BBB, etc. And that the FDA didn’t choose to measure this in safety trials. I’ll still entertain the possibility of having the vaccine myself once I can see long term results. Nope, don’t trust any publication by the FDA. They’re as reliable as a publication from InfoWars.
 
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DRay827

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And what about the scientist that study and question the safety of these vaccine?
Big Pharma has given us no reason to blindly trust them.
I consider myself pretty skeptical of Big Pharma, but this graph is all I need to believe them on the covid vaccine. Sure, there's been some instances of people reacting poorly to their shots, but nowhere near the amount to make me concerned about safety.

E3EVCpMXoAQpQMx
 

EriktheRed

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I consider myself pretty skeptical of Big Pharma, but this graph is all I need to believe them on the covid vaccine. Sure, there's been some instances of people reacting poorly to their shots, but nowhere near the amount to make me concerned about safety.

E3EVCpMXoAQpQMx
The only potential issue is long-term effects which are unlikely, but we wouldn't know already. The other thing is benefit to young people vs any associated impacts.
 

Oldschool1964

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I consider myself pretty skeptical of Big Pharma, but this graph is all I need to believe them on the covid vaccine. Sure, there's been some instances of people reacting poorly to their shots, but nowhere near the amount to make me concerned about safety.

E3EVCpMXoAQpQMx
Or maybe the population has reached herd immunity? Anyone that recovered from Covid-19 now has immunity from months to years, to their entire lifetime.



PS - if you recovered from Covid-19 and received the vaccine, it probably was a total waste.
 

ScarletNCream

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I’m trying to wrap my brain around being sick and stupid enough to have a bias towards wanting the vaccines to be bad. Those things are literally saving hundreds of thousands of American lives right now and we have people on the board that get giddy whenever they can find any sort of shitty article trying to convince them the vaccine is bad. You suck at life
 

damcde

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Or maybe the population has reached herd immunity? Anyone that recovered from Covid-19 now has immunity from months to years, to their entire lifetime.



PS - if you recovered from Covid-19 and received the vaccine, it probably was a total waste.

Not really, there have been several papers like the one below that shows that 1. The vaccine boosts the antibody response substantially, and 2. That those with two doses of the vaccine typically have much higher antibody levels than those with natural infection. Now we can have a discussion about whether or not you need the second dose if you have already been vaccinated which most research show that you don’t.

 

Oldschool1964

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Not really, there have been several papers like the one below that shows that 1. The vaccine boosts the antibody response substantially, and 2. That those with two doses of the vaccine typically have much higher antibody levels than those with natural infection. Now we can have a discussion about whether or not you need the second dose if you have already been vaccinated which most research show that you don’t.

But what is "substantially"? Do you think that recovering from the Covid-19 virus means that you're immune from it for your entire lifetime?
 
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williamsonframe

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I’m trying to wrap my brain around being sick and stupid enough to have a bias towards wanting the vaccines to be bad. Those things are literally saving hundreds of thousands of American lives right now and we have people on the board that get giddy whenever they can find any sort of shitty article trying to convince them the vaccine is bad. You suck at life
Not as sick as you fvcks hoping the covid body count would rise so you can justify your political gods lockdowns and masks.
 

damcde

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My take (and for starters I think you were going for ‘empirical’ but got tricked out of it by spellcheck) is rather they were collecting empirical evidence of a finding that was Not supposed to be a result of the vaccines, but in fact showed the vaccine spike protein Did enter the bloodstream, cross BBB, etc. And that the FDA didn’t choose to measure this in safety trials. I’ll still entertain the possibility of having the vaccine myself once I can see long term results. Nope, don’t trust any publication by the FDA. They’re as reliable as a publication from InfoWars.

There is a huge difference between showing that the spike protein crosses the BBB by doing an I.v. Injection of a bunch of purified protein and with an intramuscular injection. I can give a mouse a bunch of LCMV iv, and it will cross the BBB resulting in disease. But if I gave the same dose i.m. they wouldn’t even get sick.
 

williamsonframe

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I mean cool story but nobody did that, you accused people of that at the time and we all laughed at you
You can tell yourself that. But watching states opening up or seeing people celebrate holidays infuriated people and couldn't wait to see the death rate spike. Shoot I watch @steinek11 celebrate rss members death today. He your people.
 

damcde

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But what is "substantially"? Do you think that recovering from the Covid-19 virus means that you're immune from it for your entire lifetime?

I linked the paper for you. It went up about 5 logs. The people with natural infection actually had levels that were the same as uninflected individuals with one dose of the vaccine. We know that the vaccine is much more effective after the second dose, so i would say pretty substantial.

As for the immune for your lifetime, if it is like every other respiratory virus, including other coronaviruses then no, you won’t be completely immune for your lifetime. We get reinfected each year by the same cold viruses. There was a great paper that came out a year ago showing that within a year most people would get reinfected with the common coronavirus strains year after year. That said, even if you get reinfected, protection against severe disease should last much much longer. However, that changes when you talk about those with weakened immune responses, which includes those 65 and above.
 
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steinek11

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You can tell yourself that. But watching states opening up or seeing people celebrate holidays infuriated people and couldn't wait to see the death rate spike. Shoot I watch @steinek11 celebrate rss members death today. He your people.
Didn’t celebrate shit.
Stubborn and dumb ass did a stubborn dumb ass thing and died. Should serve as a lesson to the rest of us. Don’t want to see anyone die. He did not have to die he made the choice to let himself get killed most likely because of his politics
 
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Cash68847

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The alt right’s infatuation with scapegoating Fauci over Dear Leader’s failures is embarrassing at this point
Why can’t you separate the two? I’ve always been a believer the government will drop the ball regardless whatever party or President is in charge when shit hits the fan. Fauci looks worse to me than Trump at this point. Those emails are pretty bad. It looks like his agenda was to save his ass and push his narrative using big tech.
 

Hardlyboy

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Why can’t you separate the two? I’ve always been a believer the government will drop the ball regardless whatever party or President is in charge when shit hits the fan. Fauci looks worse to me than Trump at this point. Those emails are pretty bad. It looks like his agenda was to save his ass and push his narrative using big tech.
Ok
 
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Cash68847

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It their new Hillary,but they know they have to work harder to attack his character because he isn't Hillary.
Look at the emails and his flip flopping and outright lies to cover his ass during the pandemic. The guy is a complete fraud. It’s not very hard to see unless you’re so invested in hating Trump. It’s only a matter of time before Biden tells him to hit the road.
 
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