I wouldn't bet on Nebraska covering, but I would bet the hell out of the over.
1. Scoring is up all over college football, and even great defenses are struggling.
2. Ohio State will score at will on the Huskers.
3. Ohio State has 7 new starters on defense including a very raw interior of their defensive line. From a matchup standpoint, you're looking at Wilson, Farniok, and Jurgens, with 68 career combined starts facing 2 new D-tackles with 0 starts.
To make a long story short, I think Nebraska will have some success moving the football vs Ohio State, at least a lot more than last season.